Pruritus, commonly known as ITCH, is a sensation that causes the desire or reflex to scratch. ITCHING can range from mild to severe and can be caused by a variety of conditions such as allergies, infections, skin diseases, and other medical conditions. Pruritus is a symptom of many different medical conditions and can be localized to one area of the body or generalized throughout the body. Treatment for pruritus depends on the underlying cause and may include topical creams, oral medications, and lifestyle changes.