The term PROFANE LEAST is an oxymoron, meaning that it combines two words that have opposite meanings. The word profane means something that is not holy or sacred, while the word least means the smallest amount or degree. This oxymoron is used to describe something that is not holy or sacred, but still has a small amount of holiness or sacredness. The crossword solution for this term is HOLIEST, which means having the most holiness or sacredness.