The crossword solution for the term 'Prepare to Score from Third, Say' is TAGUP, which is a five-letter word. TAGUP is a baseball term that means to prepare to score from third base. This phrase is often used when a runner is on third base and the batter hits a ball that could potentially allow the runner to score. The batter must be prepared to run to first base in case the ball is caught, while the runner on third must be ready to score if the ball is not caught.