The crossword solution for the term 'PREFIX WITH NOIR' is NEO, which is a three-letter prefix. NEO is derived from the Greek word neos, meaning 'NEW'. It is commonly used as a prefix in English to denote something that is NEW or modern. When combined with the French word NOIR, meaning 'BLACK', NEO-NOIR is a genre of film and literature that combines elements of crime fiction and film NOIR. NEO-NOIR often features stories of moral ambiguity, crime, and violence.