The term 'prefix with -drome' refers to words that have the same prefix and end with '-drome'. The two crossword solutions for this term are 'aero' and 'velo'. 'Aero' is a prefix derived from the Greek word for air, and it is used to refer to things related to the air or atmosphere. 'Velo' is a prefix derived from the Latin word for speed, and it is used to refer to things related to speed or velocity.