The term 'prefix with dermis' refers to two medical terms: epidermis (EPI) and endodermis (ENDO). Epidermis is the outermost layer of the skin, while endodermis is the innermost layer of the skin. Both epidermis and endodermis are composed of several layers of cells that provide protection from the environment and regulate the body's temperature. The epidermis is the most visible layer of the skin and is responsible for providing protection from the sun, wind, and other environmental factors. The endodermis, on the other hand, is responsible for regulating the body's temperature and providing a barrier between the internal organs and the external environment.