The crossword solution for the term 'prefix with bot' is 'NANO'. The prefix 'nano-' is derived from the Greek word for 'DWARF' and is used to denote a very small size. It is often used in scientific contexts to refer to objects that are smaller than a micrometer, or one millionth of a meter. In the context of robotics, the prefix 'nano-' is used to refer to robots that are extremely small in size. Thus, the term 'prefix with bot' can be interpreted as referring to a robot that is nano-sized.