Powerful Cleaner is a term used to describe a cleaning agent that is strong enough to remove tough stains and dirt. Two common examples of powerful cleaners are Ammonia (7 letters) and LYE (3 letters). Ammonia is a colorless gas with a strong odor that is often used in household cleaning products. LYE is a caustic alkali that is used in the manufacture of soaps and detergents. Both Ammonia and LYE are effective at removing dirt and stains, but they should be used with caution as they can be hazardous if not handled properly.