The term 'PORT ON LAKE ONTARIO' can be solved by the six-letter word 'OSWEGO'. Oswego is a city located in Oswego County, New York, on the southeastern shore of Lake Ontario. It is the largest city in the county and the 19th most populous city in the state. The city is known for its harbor, which is one of the busiest ports on the Great Lakes. Oswego is also home to the State University of New York at Oswego, which is one of the oldest public universities in the United States.