The crossword solution for the term 'Pope First' is PETER. Peter was one of the twelve apostles of Jesus Christ and is considered to be the first Pope of the Catholic Church. He is also known as the 'Prince of the Apostles' and is venerated as a saint in both the Eastern Orthodox and Roman Catholic Churches. He is credited with founding the Church of Antioch and is believed to have been martyred in Rome during the reign of Nero.