The term 'POISONOUS SECRETION' can be summarized by the crossword solution 'VENOM' which is a five letter word. VENOM is a type of poisonous secretion that is produced by certain animals, such as snakes, spiders, and scorpions, as a defense mechanism or to capture prey. It is typically injected into its target through the use of fangs, spines, or stingers. VENOM can cause serious injury or even death if not treated properly.