Poisoning is a serious health issue that can be caused by a variety of substances. The two crossword solutions for the term 'poisoning' are LEAD and PTOMAINE. LEAD poisoning is caused by exposure to LEAD, which can be found in paint, dust, soil, and water. Ptomaine poisoning is caused by eating food contaminated with certain types of bacteria. Both types of poisoning can cause serious health problems, including organ damage, neurological issues, and even death.