Peyton's brother ELI is a three-letter answer to the crossword puzzle. ELI Manning is an American football quarterback who played for the New York Giants of the National Football League (NFL) from 2004 to 2019. He is the younger brother of former NFL quarterback Peyton Manning, who played for the Indianapolis Colts and Denver Broncos. ELI was selected first overall in the 2004 NFL Draft by the San Diego Chargers and was traded to the Giants shortly after. He led the Giants to two Super Bowl victories in 2008 and 2012.