Pandora's Boxful, mostly' refers to the myth of Pandora's Box. In Greek mythology, Pandora was given a box by Zeus and told not to open it. However, she was curious and opened it, releasing all the evils of the world. The only thing left in the box was hope. The term 'Pandora's Boxful, mostly' is used to refer to a situation that has been made worse by someone's actions. The crossword solutions for this term are ILLS, which stands for illnesses, troubles, and sorrows. These are all the negative consequences of Pandora's curiosity.