The term 'Isthmi' is a reference to two important canals, the Panama Canal and the Suez Canal. The Panama Canal is a 48-mile waterway connecting the Atlantic and Pacific Oceans, located in Central America. It was built by the United States between 1904 and 1914 and is now managed by the Republic of Panama. The Suez Canal is a man-made waterway connecting the Mediterranean Sea and the Red Sea, located in Egypt. It was constructed by Ferdinand de Lesseps between 1859 and 1869 and is now owned and operated by the Suez Canal Authority. Both canals are important for international trade and transportation.