Pakistan's largest city is Karachi, which is located in the southern part of the country. It is the most populous city in Pakistan and the capital of Sindh province. It is a major seaport and financial hub, as well as a cultural and economic center. Karachi is home to many industries, including textiles, pharmaceuticals, steel, and automotive manufacturing. It is also a major tourist destination, with its beaches, historical sites, and vibrant nightlife.