The crossword solution for the term 'Painkiller Choice' is CODEINE, which is a seven-letter word. CODEINE is an opioid analgesic medication used to treat mild to moderate pain and is also used as a cough suppressant. It is typically taken orally in the form of tablets or syrup, and is also available in combination with other medications such as paracetamol and ibuprofen. CODEINE is a controlled substance and can be addictive if taken in large doses or for long periods of time.