The Ozone Problem is a global environmental issue caused by the release of ozone-depleting substances into the atmosphere. These substances, such as chlorofluorocarbons, have been linked to the depletion of the ozone layer, which protects the Earth from harmful ultraviolet radiation. The term 'HOLE' in this context refers to the Antarctic Ozone HOLE, an area of the ozone layer that has been particularly affected by the Ozone Problem.