The term 'over 21' is often used to refer to someone who is considered an ADULT. This term is usually used in the context of LEGAL age, meaning that someone who is over 21 is legally allowed to do certain activities such as purchase alcohol or gamble. The crossword solutions for this term are ADULT (5 letters), LEGAL (5 letters), and OFAGE (5 letters). All three of these words can be used to describe someone who is over 21 years old.