Oregon City on the Willamette is the largest city in Oregon, located in the Willamette Valley region of the state. The city is situated at the confluence of the Willamette and Clackamas Rivers, about 50 miles south of Portland. The city is the county seat of Clackamas County and is known for its historic downtown area and its location on the banks of the Willamette River. The city's name comes from the Native American word for 'meeting place' and was first settled in 1829. Eugene, which has a population of over 160, 000, is the second largest city in Oregon and is located about 100 miles south of Oregon City on the Willamette.'