The crossword solution for the term OPUS (WORK OF GOD) is DEI. DEI is an abbreviation of the Latin phrase 'Deus Est Ineffabilis' which translates to 'GOD is Ineffable'. This phrase is often used to refer to the works of GOD, such as the creation of the universe and all living things. The term OPUS is also used to refer to a great work of art or literature, such as a masterpiece painting or a classic novel.