The term 'OPPOSITE OF BLESSING' can be answered with the five-letter word 'CURSE'. A CURSE is a type of negative energy or bad luck that is believed to be inflicted upon someone or something. It is often seen as a form of supernatural punishment, and is usually invoked by a person or group of people. Curses are often used in literature, mythology, and folklore, and can be seen as a way of expressing anger or frustration.