The Otoe were a Native American tribe that were once buffalo hunters. They lived in the Great Plains region of the United States and were known for their nomadic lifestyle. The Otoe were part of the larger Sioux Nation and were closely related to the Iowa, Missouri, and Ponca tribes. They were skilled hunters and used buffalo hides for clothing and shelter. The Otoe were eventually forced to move to Oklahoma and Nebraska due to the expansion of the United States.