The crossword solutions for the term 'ONE DOWN IN THE MOUTH' are UVULA (5 letters) and TONSIL (6 letters). The UVULA is a small, fleshy extension of the soft palate located at the back of the throat. It is composed of connective tissue and mucous membrane and is responsible for producing saliva. The tonsils are two small masses of lymphatic tissue located on either side of the throat. They are part of the body's immune system and help to protect against infection.