The term 'NUMERO UNO' is a Spanish phrase meaning 'number ONE' and is often used to refer to someone or something that is the BEST or most important. The crossword solutions for this term include PRIMO (5 letters), BEST (4 letters), ONE (3 letters), ONTOP (5 letters), THEBEST (7 letters), FOREMOST (8 letters), HEADHONCHO (10 letters), and PERSONALITY (11 letters). All of these words can be used to describe someone or something that is the BEST, most important, or highest ranking.