No-hoper is a term used to describe someone who has no chance of success in a particular endeavor. It is often used to describe someone who has given up hope of achieving something, or someone who is not expected to succeed. The term is derived from the phrase 'no hope, ' which implies that the person has no chance of succeeding. The crossword solution for the term 'no-hoper' is 'LOSER, ' which is another term for someone who has no chance of success.