The crossword solution for the term NEW (PREF.) is NEO, which is a three letter word. NEO is a prefix that is derived from the Greek word 'neos' meaning 'NEW'. It is commonly used in English to refer to something that is NEW or modern. NEO is often used in scientific terms, such as neoplasm, which refers to a NEW growth of abnormal cells. It is also used in technology, such as in the term 'neobank', which refers to a digital-only bank.