The crossword solution for the term 'NEW AS A PREFIX' is NEO, which is a three-letter word. NEO is a prefix that is used to denote something that is NEW or recent. It is derived from the Greek word 'neos, ' which means 'NEW.' NEO is commonly used in scientific and medical terms, such as neoplasia, which refers to the abnormal growth of cells. It is also used in technology, such as the term 'neobank, ' which is a digital-only bank.