The term MUSICIANS PLAY THEM can be summarized by the crossword solution SETS, which is a four-letter word. Sets are collections of musical instruments that are typically used by musicians in order to create music. They are usually composed of drums, cymbals, and other percussion instruments, as well as guitars, keyboards, and other stringed instruments. Sets are often used in live performances, recordings, and rehearsals, and they are essential for any musician who wants to create a full sound.