Muscle pain is a common symptom that can be caused by a variety of conditions. It can range from mild to severe and can be localized or widespread. The three crossword solutions for the term muscle pain are CRAMP, myalgia, and ACHE. CRAMP is a sudden, involuntary contraction of a muscle or group of muscles that can cause intense pain. Myalgia is a general term for muscle pain that can be caused by overuse, injury, or infection. ACHE is a dull, continuous pain that can be localized or widespread.