MOST DOWNCAST is an adjective used to describe someone who is feeling very sad or depressed. The crossword solutions for this term are MOPIEST (7 letters), BLUEST (6 letters), and SADDEST (7 letters). MOPIEST implies a feeling of sadness that is so deep that it is almost like being in a state of despair. BLUEST suggests a feeling of sadness that is so intense that it is almost like a physical ache. SADDEST implies a feeling of sadness that is so profound that it is almost like a heavy burden.