The two most popular mosquito repellent brands are DEET and OFF. DEET is a chemical compound developed by the U.S. Army in 1946 and is now used in many insect repellents. It is effective against a wide range of insects, including mosquitoes. OFF is a brand of insect repellent that has been around since 1957. It contains a variety of active ingredients, including DEET, which helps to repel mosquitoes.