Minimal resistance is a term used to describe a situation in which the least amount of effort is required to achieve a desired outcome. The crossword solution for minimal resistance is 'EASE, ' which implies that the task or goal can be accomplished with minimal effort. This term is often used in business and economics to describe a situation in which the least amount of resources are used to achieve the desired result. It is also used in other contexts, such as engineering, to describe a situation in which the least amount of energy is used to achieve a desired outcome.