The Midwest region of the United States is comprised of several states, including Iowa (4 letters), Ohio (4 letters), Illinois (8 letters), and KANSAS (6 letters). Iowa is known for its rolling hills and agricultural production, while Ohio is home to many major cities and industries. Illinois is a major hub for transportation and commerce, and KANSAS is known for its vast prairies and plains. All four of these states are part of the Midwest region of the United States.