Mental weariness is a state of exhaustion that can be caused by a variety of factors, including physical and emotional stress. It is often characterized by FATIGUE, ENNUI, DISINTEREST, and BOREDOM. FATIGUE is a feeling of extreme tiredness or exhaustion, ENNUI is a feeling of listlessness or apathy, DISINTEREST is a lack of enthusiasm or interest, and BOREDOM is a feeling of being uninterested or unengaged. All of these feelings can contribute to mental weariness.