Medical disappointment is a term used to describe the feeling of discouragement and frustration when a medical condition does not improve or worsens after treatment. It is often experienced by patients who have been diagnosed with a chronic illness or have undergone a medical procedure with the expectation of a positive outcome. The term RELAPSE, which is a seven-letter crossword solution for the term MEDICAL DISAPPOINTMENT, refers to the recurrence of a medical condition after a period of improvement.