Meddle (in) is an idiom that means to interfere in something without being asked or invited. It is often used in a negative context, as it implies that someone is intruding on another person's business. The crossword solution for the term MEDDLE (IN) is MESS, which is a synonym for meddle. It is used to describe a situation where someone has caused confusion or chaos by interfering in something they were not asked to be involved in.