Mamie Husband of refers to Mamie Eisenhower, the wife of President Dwight D. Eisenhower. Mamie Eisenhower was a popular First Lady of the United States from 1953 to 1961 and her husband's nickname for her was 'Mamie'. The crossword solution for Mamie Husband of is IKE, which is the nickname of Dwight D. Eisenhower. Dwight D. Eisenhower was the 34th President of the United States and served two terms from 1953 to 1961.