The crossword solution for the term 'Malady Plant' is 'EDEMA, ' which is a five-letter word. EDEMA is a medical condition in which fluid accumulates in the body's tissues, causing swelling. It is most commonly caused by an imbalance in the body's electrolytes, but can also be caused by certain medications, allergies, or infections. EDEMA can be treated with diuretics, lifestyle changes, and other medications.