Makes weary is a phrase that describes the feeling of being exhausted or drained. The crossword solutions for this term are TIRES, IRKS, and JADES. TIRES is a verb meaning to exhaust or deplete one's energy or strength. IRKS is a verb meaning to irritate or annoy someone. JADES is a verb meaning to make someone or something dull or uninteresting. All three words can be used to describe the feeling of being weary.