The crossword solution for the term 'MAKE BIG BUCKS' is 'CLEANUP'. This means that one way to make big bucks is to do CLEANUP work. CLEANUP work can involve a variety of tasks, such as cleaning up after construction projects, cleaning up after events, or even cleaning up hazardous materials. CLEANUP work can be done on a freelance basis or as part of a larger organization. It is a great way to make money quickly and can be very rewarding.