The crossword solution for the term 'MAKE A HUGE PROFIT' is 'CLEANUP'. This term can be interpreted in a variety of ways, but it generally refers to the process of making a large amount of money through careful management and organization. It could refer to the process of streamlining a business or organization to make it more efficient and profitable, or it could refer to the process of investing in stocks or other financial instruments to generate a large return on investment. In any case, it implies that a great deal of effort and planning has gone into making a large profit.