The term 'make a difference' is often used to describe the impact that an individual or group can have on a situation. The five crossword solutions for this term are ALTER (5 letters), AFFECT (6 letters), TELL (4 letters), COUNT (5 letters), and MATTER (6 letters). ALTER means to change something, AFFECT means to influence something, TELL means to communicate something, COUNT means to be significant, and MATTER means to be important. Together, these words suggest that making a difference involves changing, influencing, communicating, being significant, and being important.