The term 'MAJOR NAME IN CARDS' can be solved by the four letter word 'AMEX'. American Express, commonly known as AMEX, is a multinational financial services corporation. It is one of the 30 components of the Dow Jones Industrial Average and is best known for its charge card, credit card, and traveler's cheque businesses. AMEX is one of the most widely accepted credit cards in the world, and is a major name in the credit card industry.