The term 'Major Muddle' is a combination of two words, 'MESS' and 'SNAFU'. MESS is a four letter word meaning a state of confusion or disorder, while SNAFU is a five letter acronym for 'Situation Normal All Fouled Up', which is a military term used to describe a chaotic situation. Together, the two words form the phrase 'Major Muddle', which is used to describe a situation that is extremely chaotic and disorganized.