The crossword solution for the term 'MAJOR CLOSING' is ETTE, which is a four letter word. ETTE is a French suffix that is used to denote a female version of a word, such as 'WAITRESS' being the female version of 'WAITER'. It is also used to create diminutives, such as 'kitchenette' being a smaller version of a kitchen. In this case, 'MAJOR closing' could be referring to a female manager or supervisor who is responsible for closing a business.