The term 'Made the Most Of' can be broken down into two crossword solutions: 'USED' and 'ranwith'. 'USED' is a 4-letter word meaning to take advantage of something, while 'ranwith' is a 7-letter word meaning to take advantage of an opportunity. Together, these two words suggest that someone has taken advantage of an opportunity to make the most of a situation. This phrase is often USED to describe someone who has made the best out of a difficult or challenging situation.