The capital of Macedonia is Skopje, which has 6 letters. Pella, another city in Macedonia, also has 5 letters. Skopje is the largest city and the political, cultural, economic, and academic center of the country. It is located on the upper course of the Vardar River and is home to roughly a quarter of the nation's total population. Pella is an ancient city located in the region of Macedonia, and was the capital of the kingdom of Macedon in the 4th century BC. It is now an archaeological site and a popular tourist destination.