The term 'Lose Water' can be solved by the 8-letter word 'PERSPIRE'. Perspiration, or sweating, is a natural process that helps regulate body temperature. It is the body's way of cooling itself down when it gets too hot. Perspiration is caused by the release of water and salt from the sweat glands in the skin. When the body loses water through perspiration, it is important to replace it with fluids to prevent dehydration.