The crossword solution for the term 'Lose Skin' is 'PEEL'. This term is used to describe the process of removing the outer layer of skin from a surface or object. It is often used in reference to the shedding of dead skin cells from the body, which is a natural process that occurs as part of the skin's regeneration cycle. Peeling can also refer to the removal of paint, varnish, or other coatings from a surface.